Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | TACR3 | P29371 | 1/20 | 0.46 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7065609 | 1.00 | ATM (0.48) | ATMTACR1HDAC1HDAC6TACR3 | |
| SCHEMBL4324281 | 0.80 | CTSL (0.51) | TACR1HDAC1HDAC6SSTR1CTSL | |
| SCHEMBL4324286 | 0.80 | CTSL (0.51) | TACR1HDAC1HDAC6SSTR1CTSL | |
| SCHEMBL12971777 | 0.79 | ATM (0.55) | ATMSSTR1CTSLCTSSCTSK | |
| SCHEMBL1505365 | 0.79 | ATM (0.55) | ATMSSTR1CTSLCTSSCTSK | |
| SCHEMBL27564744 | 0.79 | SSTR1 (0.71) | TACR1SSTR1CA2 | |
| SCHEMBL27584500 | 0.79 | SSTR1 (0.71) | TACR1SSTR1CA2 | |
| SCHEMBL394603 | 0.79 | PTPRB (0.52) | ATMCTSLCTSSCTSKALDH1A1 | |
| SCHEMBL394602 | 0.79 | PTPRB (0.52) | ATMCTSLCTSSCTSKALDH1A1 | |
| SCHEMBL394660 | 0.78 | F11 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602849-B1 | Cyclic somatostatin analogs | SOCIETE DE CONSEILS DE RECHERCHE ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) | 2003-08-05 | — | — | US | disclosed |
| EP-1086131-A1 | CYCLIC SOMATOSTATIN ANALOGS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999065942-A1 | CYCLIC SOMATOSTATIN ANALOGS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 1999-12-23 | — | — | WO | disclosed |