Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5455057 | 0.84 | LMNA (0.48) | LMNAALDH1A1SMN1; SMN2PTPN1CYP3A4 | |
| SCHEMBL1543403 | 0.79 | LMNA (0.50) | LMNAALDH1A1SMN1; SMN2CYP3A4USP2 | |
| SCHEMBL426007 | 0.79 | — | — | |
| SCHEMBL18769646 | 0.79 | — | — | |
| SCHEMBL4650002 | 0.77 | USP2 (0.31) | SMN1; SMN2PTPN1CYP3A4USP2 | |
| SCHEMBL28277801 | 0.77 | SMN1; SMN2 (0.48) | LMNAALDH1A1SMN1; SMN2PTPN1CYP3A4 | |
| SCHEMBL19962777 | 0.75 | LMNA (0.50) | LMNAALDH1A1PSMD14PLA2G1BMMP2 | |
| SCHEMBL9488939 | 0.75 | THRB (0.43) | LMNAALDH1A1SMN1; SMN2PTPN1CYP3A4 | |
| SCHEMBL561350 | 0.75 | SMN1; SMN2 (0.36) | LMNAALDH1A1SMN1; SMN2PSMD14PLA2G1B | |
| SCHEMBL6437172 | 0.75 | LMNA (0.44) | LMNAALDH1A1CYP3A4TSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192198-B1 | PROCESS FOR MAKING GRAFT POLYOLS USING T-AMYL PEROXY FREE RADICAL INITIATOR | BASF CORP (US) | 2003-05-28 | — | — | EP | disclosed |