SCHEMBL7065722

SCHEMBL7065722

Nc1cccc2c(O)[c]c(S(=O)(=O)O)cc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.49
AURKA O14965 1/20 0.40
AURKB Q96GD4 1/20 0.40
ALDH1A1 P00352 6/20 0.38
HSD17B10 Q99714 5/20 0.38
TSHR P16473 4/20 0.38
CYP3A4 P08684 3/20 0.38
HPGD P15428 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
SENP3 Q9H4L4 2/20 0.36
SENP2 Q9HC62 2/20 0.36
SENP1 Q9P0U3 2/20 0.36
SUMO2 P61956 1/20 0.36
SUMO1 P63165 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
THRB P10828 1/20 0.35
ALOX15 P16050 1/20 0.35
CASP1 P29466 1/20 0.35
RECQL P46063 1/20 0.35
PARP1 P09874 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7067393 0.79 HSD17B10 (0.38) TTRAURKAAURKBALDH1A1HSD17B10
SCHEMBL7065409 0.76 AURKA (0.39) TTRAURKAAURKBALDH1A1HSD17B10
SCHEMBL6630742 0.75 CYP2D6 (0.44) ALDH1A1HSD17B10TSHRHPGDTDP1
Sulfuric Acid SCHEMBL8642510 0.74 TTR (0.72) TTRAURKAAURKBALDH1A1HSD17B10
SCHEMBL11595998 0.72 AURKA (0.51) TTRAURKAAURKBALDH1A1HSD17B10
SCHEMBL7063818 0.71
SCHEMBL2912144 0.71 NSD2 (0.33) ALDH1A1HSD17B10CASP6NSD2
SCHEMBL2472818 0.71 NT5E (0.54) ALDH1A1HSD17B10TSHRCYP3A4HPGD
SCHEMBL2152539 0.71 CASP6 (0.54) ALDH1A1HSD17B10TSHRCYP3A4HPGD
SCHEMBL155753 0.70 HSD17B10 (0.53) TTRAURKAAURKBALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0864614-A1 Mixtures of azo dyes, azo dyes, process for their preparation and the use thereof Ciba SC Holding AG (CH) 1998-09-16 EP claimed
EP-0765965-B1 Process for deying synthetic fibrous polyamid materials DYSTAR TEXTILFARBEN GMBH & CO (DE) 2003-06-04 EP disclosed
US-5997587-A Azo dye mixtures, azo dyes, processes for their preparation, and their use CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-12-07 US disclosed
EP-0765918-B1 Reactive dye preparations DYSTAR TEXTILFARBEN GMBH & CO (DE) 1999-07-28 EP disclosed
US-5810890-A USING SPECIFIED MIXTURE OF DYES; INCREASED BRIGHTNESS AND LEVELNESS DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1998-09-22 US disclosed
EP-0864614-A1 Mixtures of azo dyes, azo dyes, process for their preparation and the use thereof Ciba SC Holding AG (CH) 1998-09-16 EP disclosed
EP-0864614-A1 Mixtures of azo dyes, azo dyes, process for their preparation and the use thereof Ciba SC Holding AG (CH) 1998-09-16 EP disclosed
US-5803930-A MIXTURE OF TWO DIFFERENT WATER SOLUBLE DYES; DYEING SYNTHETIC POLYAMIDES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1998-09-08 US disclosed
EP-0765965-A2 Process for deying synthetic fibrous polyamid materials DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1997-04-02 EP disclosed
EP-0765918-A2 Reactive dye preparations DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1997-04-02 EP disclosed