Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | MELK | Q14680 | 1/20 | 0.33 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.33 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11875966 | 0.83 | TTR (0.41) | AURKAAURKBTTRALDH1A1HSD17B10 | |
| SCHEMBL8377402 | 0.78 | NT5E (0.61) | ALDH1A1HSD17B10NT5ECASP6CYP2C9 | |
| SCHEMBL1413164 | 0.77 | NT5E (0.39) | ALDH1A1HSD17B10NT5E | |
| SCHEMBL7065722 | 0.76 | TTR (0.49) | AURKAAURKBTTRALDH1A1HSD17B10 | |
| SCHEMBL7068945 | 0.75 | CASP6 (0.50) | ALDH1A1HSD17B10TSHRCASP6CYP2C19 | |
| SCHEMBL11595998 | 0.74 | AURKA (0.51) | AURKAAURKBTTRALDH1A1HSD17B10 | |
| SCHEMBL6630742 | 0.73 | CYP2D6 (0.44) | ALDH1A1HSD17B10TSHRTDP1CASP6 | |
| SCHEMBL11433276 | 0.71 | AURKA (0.47) | AURKAAURKBTTRALDH1A1HSD17B10 | |
| SCHEMBL3928588 | 0.71 | NT5E (0.70) | AURKAAURKBALDH1A1HSD17B10TSHR | |
| SCHEMBL31336134 | 0.71 | NT5E (0.70) | AURKAAURKBALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765965-B1 | Process for deying synthetic fibrous polyamid materials | DYSTAR TEXTILFARBEN GMBH & CO (DE) | 2003-06-04 | — | — | EP | disclosed |
| EP-0765918-B1 | Reactive dye preparations | DYSTAR TEXTILFARBEN GMBH & CO (DE) | 1999-07-28 | — | — | EP | disclosed |
| US-5810890-A | USING SPECIFIED MIXTURE OF DYES; INCREASED BRIGHTNESS AND LEVELNESS | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 1998-09-22 | — | — | US | disclosed |
| US-5803930-A | MIXTURE OF TWO DIFFERENT WATER SOLUBLE DYES; DYEING SYNTHETIC POLYAMIDES | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 1998-09-08 | — | — | US | disclosed |
| EP-0765918-A2 | Reactive dye preparations | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 1997-04-02 | — | — | EP | disclosed |
| EP-0765965-A2 | Process for deying synthetic fibrous polyamid materials | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 1997-04-02 | — | — | EP | disclosed |