Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585784 | 0.93 | PTPN1 (0.32) | PTPN1ANO1 | |
| SCHEMBL6583954 | 0.87 | PTPN1 (0.33) | PTPN1 | |
| SCHEMBL6579735 | 0.86 | PTPN1 (0.31) | PTPN1ANO1 | |
| SCHEMBL6583841 | 0.80 | PSEN1 (0.37) | PTPN1ANO1 | |
| SCHEMBL6580415 | 0.78 | PTPN1 (0.37) | PTPN1 | |
| SCHEMBL4213178 | 0.72 | PPARG (0.33) | — | |
| SCHEMBL6579684 | 0.72 | PTPN1 (0.38) | PTPN1ANO1 | |
| SCHEMBL6584368 | 0.72 | LMNA (0.35) | PTPN1ANO1 | |
| SCHEMBL6580469 | 0.72 | PTPN1 (0.37) | PTPN1ANO1 | |
| SCHEMBL6585735 | 0.69 | PTPN1 (0.33) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6599925-B2 | Cardiovascular disorders; anticancer agents | WYETH | 2003-07-29 | — | — | US | disclosed |
| US-20030018067-A1 | Substituted naphthyl benzofuran derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) | WYETH | 2003-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018067-A1 | Substituted naphthyl benzofuran derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) | F2R, SERPINE1, SERPINC1 | PTPN1 1287/4885ANO1 3199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.