Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.41 |
| ▸ | TPH1 | P17752 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7069548 | 0.95 | PDE10A (0.42) | SMN1; SMN2HTTSTAT3PDE10ASCN9A | |
| SCHEMBL7604848 | 0.93 | MGAM (0.43) | SMN1; SMN2HTTSTAT3PDE10ATPH1 | |
| SCHEMBL7065961 | 0.89 | MME (0.40) | SMN1; SMN2HTTSTAT3PDE10ATPH1 | |
| SCHEMBL7067687 | 0.86 | MGAM (0.41) | SMN1; SMN2HTTSTAT3PDE10ATPH1 | |
| SCHEMBL7068772 | 0.86 | PDE10A (0.42) | SMN1; SMN2HTTSTAT3PDE10ASCN9A | |
| SCHEMBL7067709 | 0.86 | MEN1 (0.41) | PDE10ASCN9ASIRT2MMEACE | |
| SCHEMBL7065979 | 0.85 | MME (0.42) | SMN1; SMN2HTTSTAT3PDE10ATPH1 | |
| SCHEMBL7069751 | 0.84 | SCN9A (0.45) | SMN1; SMN2HTTSTAT3PDE10ATPH1 | |
| SCHEMBL7069282 | 0.84 | PPARG (0.45) | SMN1; SMN2HTTSTAT3PDE10ASCN9A | |
| SCHEMBL7066077 | 0.83 | MAOB (0.47) | TPH1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030212100-A1 | Quinoline derivatives and medicinal use thereof | MITSUI CHEMICALS, INC. (JP) | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212100-A1 | Quinoline derivatives and medicinal use thereof | PPARG, PPARD, PPARA | SMN1; SMN2 3691/4885HTT 1453/4885STAT3 260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.