Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.41 |
| ▸ | TPH1 | P17752 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066080 | 0.93 | SMN1; SMN2 (0.41) | MGAMRAB9AHTTSMN1; SMN2STAT3 | |
| SCHEMBL7065961 | 0.91 | MME (0.40) | MGAMRAB9AHTTSMN1; SMN2STAT3 | |
| SCHEMBL7069548 | 0.91 | PDE10A (0.42) | RAB9AHTTSMN1; SMN2STAT3PDE10A | |
| SCHEMBL7067687 | 0.91 | MGAM (0.41) | MGAMRAB9AHTTSMN1; SMN2STAT3 | |
| SCHEMBL7065979 | 0.90 | MME (0.42) | MGAMRAB9AHTTSMN1; SMN2STAT3 | |
| SCHEMBL7068772 | 0.88 | PDE10A (0.42) | MGAMRAB9AHTTSMN1; SMN2STAT3 | |
| SCHEMBL7067709 | 0.88 | MEN1 (0.41) | RAB9APDE10ASCN9ASIRT2MME | |
| SCHEMBL7069271 | 0.87 | PPARA (0.49) | — | |
| SCHEMBL7069282 | 0.86 | PPARG (0.45) | HTTSMN1; SMN2STAT3PDE10ASCN9A | |
| SCHEMBL7069231 | 0.86 | PPARG (0.39) | MGAMRAB9AHTTSMN1; SMN2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1266888-A1 | QUINOLINE DERIVATIVES AND MEDICINAL USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2002-12-18 | — | — | EP | disclosed |