Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7072255 | 0.94 | PDE10A (0.43) | MEN1KMT2APDE10ATRPV1CCKBR | |
| SCHEMBL7065961 | 0.90 | MME (0.40) | MEN1KMT2APDE10ATRPV1MME | |
| SCHEMBL7604848 | 0.88 | MGAM (0.43) | PDE10AMMEACECPA1ACE2 | |
| SCHEMBL7066080 | 0.86 | SMN1; SMN2 (0.41) | KMT2APDE10AMMEACECPA1 | |
| SCHEMBL7067707 | 0.85 | CYSLTR2 (0.46) | MEN1KMT2ATRPV1CCKBR | |
| SCHEMBL7069548 | 0.83 | PDE10A (0.42) | MEN1KMT2APDE10ASCN9ASIRT2 | |
| SCHEMBL7069255 | 0.82 | MME (0.39) | KMT2APDE10AMMEACECPA1 | |
| SCHEMBL7067698 | 0.82 | TRPV1 (0.43) | MEN1KMT2APDE10ATRPV1CCKBR | |
| SCHEMBL7068926 | 0.82 | TRPV1 (0.43) | MEN1KMT2APDE10ATRPV1CCKBR | |
| SCHEMBL7069697 | 0.81 | PPARG (0.41) | MEN1KMT2APDE10ATRPV1CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030212100-A1 | Quinoline derivatives and medicinal use thereof | MITSUI CHEMICALS, INC. (JP) | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212100-A1 | Quinoline derivatives and medicinal use thereof | PPARG, PPARD, PPARA | MEN1 4618/4885KMT2A 2329/4885PDE10A 2389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.