Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235377 | 0.89 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2AP2RX7 | |
| SCHEMBL7066175 | 0.89 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2AP2RX7 | |
| SCHEMBL6233904 | 0.89 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2AP2RX7 | |
| SCHEMBL7064409 | 0.87 | CNR1 (0.44) | P2RX7CNR1CNR2 | |
| SCHEMBL7066156 | 0.86 | MAPT (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2AP2RX7 | |
| SCHEMBL7061492 | 0.85 | NOTUM (0.43) | P2RX7RAB9ALMNATP53HTT | |
| SCHEMBL7107139 | 0.85 | NOTUM (0.43) | P2RX7RAB9ALMNATP53HTT | |
| SCHEMBL7068411 | 0.84 | CNR1 (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2AP2RX7 | |
| SCHEMBL7066127 | 0.82 | TSHR (0.46) | SMN1; SMN2MEN1KMT2ANPSR1HPGD | |
| SCHEMBL7066644 | 0.82 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2KMT2ARAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827954-B1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL CO (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6114543-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| US-5880291-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0827954-A1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-03-11 | — | — | EP | disclosed |