Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7062139 | 0.88 | CHRNA1 (0.43) | TSHRHSD11B1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL6232174 | 0.88 | TSHR (0.58) | TSHRHSD11B1SLC6A4SLC6A3MDM2 | |
| SCHEMBL6231109 | 0.88 | TSHR (0.58) | TSHRHSD11B1SLC6A4SLC6A3MDM2 | |
| SCHEMBL7067185 | 0.88 | TSHR (0.58) | TSHRHSD11B1SLC6A4SLC6A3MDM2 | |
| SCHEMBL7067276 | 0.86 | OPRM1 (0.43) | TSHRHSD11B1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7066810 | 0.86 | CHRM2 (0.41) | POLBHPGDKMT2ACHRM2CHRM1 | |
| SCHEMBL7067467 | 0.85 | SLC6A2 (0.44) | HSD11B1POLBSLC6A4SLC6A3SMN1; SMN2 | |
| SCHEMBL7066103 | 0.84 | ALDH1A1 (0.48) | TSHRHSD11B1POLBSMN1; SMN2MEN1 | |
| SCHEMBL7066539 | 0.83 | SLC6A9 (0.44) | TSHRHSD11B1SMN1; SMN2GAAHPGD | |
| SCHEMBL7068101 | 0.82 | SLC6A2 (0.46) | TSHRHSD11B1SLC6A4SLC6A3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827954-B1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL CO (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6114543-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| US-5880291-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0827954-A1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-03-11 | — | — | EP | disclosed |