Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13265051 | 0.93 | LTA4H (0.44) | LTA4HTSHR | |
| SCHEMBL10266294 | 0.79 | HDAC8 (0.41) | LTA4HALDH1A1NPSR1TSHRMAPT | |
| Iodide SCHEMBL28830448 | 0.76 | HDAC8 (0.39) | LTA4HALDH1A1NPSR1TSHRMAPT | |
| Iodide SCHEMBL28830447 | 0.74 | GAA (0.40) | LTA4HALDH1A1TSHRMEN1MAPT | |
| SCHEMBL15167603 | 0.74 | TSHR (0.46) | LTA4HALDH1A1LMNATSHRNR5A1 | |
| SCHEMBL11111644 | 0.72 | LTA4H (0.38) | LTA4HALDH1A1RAD52NPSR1LMNA | |
| SCHEMBL4748895 | 0.70 | L3MBTL1 (0.44) | LMNATSHRMAPTSLC6A3HDAC6 | |
| SCHEMBL28905757 | 0.70 | KCNH2 (0.63) | — | |
| SCHEMBL5288629 | 0.70 | KCNH2 (0.63) | — | |
| SCHEMBL2563319 | 0.70 | KCNH2 (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2492307-B1 | Rubber composition and pneumatic tire | GOODYEAR TIRE & RUBBER (US) | 2014-07-02 | — | — | EP | claimed |
| EP-1075966-B1 | Tire with apex rubber blend | GOODYEAR TIRE & RUBBER (US) | 2003-05-28 | — | — | EP | claimed |
| EP-0826726-B1 | A rubber compound containing aminobenzylamine | GOODYEAR TIRE & RUBBER (US) | 2001-10-24 | — | — | EP | claimed |