SCHEMBL7066332

SCHEMBL7066332

[CH2]COC(OCC)OCC

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.69
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1381944 0.86
SCHEMBL18928 0.83 THRB (1.00) THRBLMNA
SCHEMBL14763948 0.83 THRB (1.00) THRBLMNA
Hydrochloric Acid SCHEMBL31648719 0.79 THRB (0.92) THRBLMNA
Ammonia Solution, Strong SCHEMBL28342116 0.79 THRB (0.92) THRBLMNA
Hydrazine SCHEMBL28022346 0.76 THRB (0.85) THRBLMNA
Methylene Chloride SCHEMBL4405315 0.73 THRB (0.79) THRBLMNA
Alcohol SCHEMBL3582748 0.73 THRB (0.79) THRBLMNA
SCHEMBL192032 0.73
SCHEMBL17004779 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1060161-B1 MATRIX METALLOPROTEINASE INHIBITORS LEO PHARMA AS WITH SECONDARY N (DK) 2003-06-11 EP claimed
US-6277876-B1 Matrix metalloproteinase inhibitors LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) 2001-08-21 US claimed
EP-1060161-A1 MATRIX METALLOPROTEINASE INHIBITORS LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) 2000-12-20 EP claimed
WO-1999044989-A1 MATRIX METALLOPROTEINASE INHIBITORS LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) 1999-09-10 WO claimed
EP-1060161-B1 MATRIX METALLOPROTEINASE INHIBITORS LEO PHARMA AS WITH SECONDARY N (DK) 2003-06-11 EP disclosed
US-6277876-B1 Matrix metalloproteinase inhibitors LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) 2001-08-21 US disclosed