Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.31 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28792402 | 0.75 | CA12 (0.42) | CA12CA1CA2CA9EP300 | |
| SCHEMBL14955293 | 0.69 | CA12 (0.51) | CA12CA1CA2CA9EP300 | |
| SCHEMBL13749005 | 0.69 | CA12 (0.41) | CA12CA1CA2CA9KCNH2 | |
| SCHEMBL15105004 | 0.68 | CA12 (0.59) | CA12CA1CA2CA9EP300 | |
| SCHEMBL4789303 | 0.67 | ALDH1A1 (0.43) | CA12CA1CA2CA9EP300 | |
| SCHEMBL11994469 | 0.66 | CA12 (0.38) | CA12CA1CA2CA9KCNH2 | |
| SCHEMBL25614993 | 0.63 | CA12 (0.45) | CA12CA1CA2CA9EP300 | |
| SCHEMBL8303608 | 0.63 | PIM1 (0.30) | — | |
| SCHEMBL27250759 | 0.63 | CA12 (0.49) | CA12CA1CA2CA9KCNH2 | |
| SCHEMBL27250762 | 0.62 | CA12 (0.51) | CA12CA1CA2CA9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1441732-A2 | THIAZOLE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003039451-A2 | THIAZOLE PYRIDAZINONES AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-15 | — | — | WO | disclosed |