Hydroxyamine

Hydroxyamine

SCHEMBL7066541

CCOC(=O)NC=CC(=O)O.NO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 6/20 0.48
GAA P10253 3/20 0.37
ALOX15 P16050 1/20 0.37
MGAM O43451 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
ALDH1A1 P00352 5/20 0.35
RAB9A P51151 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
CYP2D6 P10635 1/20 0.34
MAPT P10636 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
APAF1 O14727 1/20 0.34
GMNN O75496 1/20 0.34
USP2 O75604 1/20 0.34
G6PD P11413 1/20 0.34
HPGD P15428 1/20 0.34
BLM P54132 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132383 0.96 HCAR2 (0.52) HCAR2GAAALOX15MGAMSI
Urea SCHEMBL11584414 0.94 HCAR2 (0.47) HCAR2GAAALOX15MGAMSI
Water SCHEMBL8356208 0.94 HCAR2 (0.50) HCAR2GAAALOX15MGAMSI
SCHEMBL19612450 0.94 HCAR2 (0.50) HCAR2GAAALOX15MGAMSI
Water SCHEMBL4421329 0.94 HCAR2 (0.50) HCAR2GAAALOX15MGAMSI
Urethane SCHEMBL5604647 0.91 ALOX15 (0.52) HCAR2GAAALOX15MGAMSI
SCHEMBL11648494 0.91 HCAR2 (0.47) HCAR2GAAMGAMSIMGAM2
Acrylic Acid SCHEMBL4558161 0.89 HCAR2 (0.46) HCAR2GAAALOX15MGAMSI
SCHEMBL8519773 0.87 HCAR2 (0.44) HCAR2GAAMGAMSIMGAM2
SCHEMBL5690799 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030166387-A1 Abrasive article with hydrophilic/lipophilic coating 3M INNOVATIVE PROPERTIES COMPANY 2003-09-04 US disclosed