Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 15/20 | 0.54 |
| ▸ | DRD3 | P35462 | 15/20 | 0.54 |
| ▸ | DRD2 | P14416 | 14/20 | 0.52 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GFER | P55789 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066698 | 0.83 | DRD4 (0.52) | DRD4DRD3DRD2HTR1AALDH1A1 | |
| SCHEMBL7068730 | 0.77 | DRD2 (0.77) | DRD4DRD3DRD2HTR1AMAPT | |
| SCHEMBL6701280 | 0.75 | DRD4 (0.75) | DRD4DRD3DRD2HTR1AMAPT | |
| SCHEMBL6647499 | 0.73 | CYP17A1 (0.51) | DRD4DRD3DRD2HTR1AMAPT | |
| SCHEMBL6703230 | 0.72 | MAPT (0.61) | MAPTGFERKDM4EGAARAD52 | |
| Hydrochloric Acid SCHEMBL6700203 | 0.72 | CYP17A1 (0.50) | DRD4DRD3DRD2HTR1AMAPT | |
| SCHEMBL7066635 | 0.71 | MAPT (0.48) | DRD4DRD3DRD2HTR1AMAPT | |
| SCHEMBL654308 | 0.71 | DRD4 (0.77) | DRD4DRD3DRD2MAPTGFER | |
| SCHEMBL22495230 | 0.70 | KDM4E (0.67) | MAPTGFERKDM4EGAARAD52 | |
| SCHEMBL12006115 | 0.70 | MAPT (0.57) | MAPTGFERKDM4EGAARAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003047575-A1 | THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-12 | — | — | WO | claimed |
| WO-2003047575-A1 | THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-12 | — | — | WO | disclosed |
| WO-2003048121-A1 | THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-12 | — | — | WO | disclosed |