Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 8/20 | 0.52 |
| ▸ | DRD3 | P35462 | 8/20 | 0.52 |
| ▸ | DRD2 | P14416 | 7/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.45 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066700 | 0.83 | DRD4 (0.54) | DRD4DRD3DRD2HTR1AALDH1A1 | |
| SCHEMBL7068726 | 0.80 | DRD2 (0.69) | DRD4DRD3DRD2HTR1APOLB | |
| SCHEMBL6701277 | 0.79 | DRD2 (0.66) | DRD4DRD3DRD2CHRNA7CHRNA10 | |
| SCHEMBL6694937 | 0.76 | ITGB3 (0.56) | HTR2AHTR2CHTR2BPOLBITGB3 | |
| SCHEMBL7253167 | 0.76 | MEN1 (0.51) | CHRNA7CHRNA10CHRNA9HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL6700195 | 0.75 | ITGB3 (0.55) | HTR2AHTR2CHTR2BPOLBITGB3 | |
| SCHEMBL2744427 | 0.75 | HTR2A (0.69) | DRD4HTR2AHTR2CHTR2BITGB3 | |
| SCHEMBL7066632 | 0.75 | MEN1 (0.46) | CHRNA7CHRNA10CHRNA9HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL9742137 | 0.74 | HTR2A (0.67) | DRD4HTR2AHTR2CHTR2BITGB3 | |
| SCHEMBL26816573 | 0.73 | KDM4E (0.56) | HTR2AHTR2CHTR2BMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003047575-A1 | THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-12 | — | — | WO | claimed |
| WO-2003047575-A1 | THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-12 | — | — | WO | disclosed |
| WO-2003048121-A1 | THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-12 | — | — | WO | disclosed |