SCHEMBL706682

SCHEMBL706682

O=S(=O)(Cl)c1ccc2c(c1)OCCO2

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PKM P14618 7/20 0.61
PKLR P30613 4/20 0.61
NPC1 O15118 1/20 0.61
RAB9A P51151 1/20 0.61
MAPT P10636 1/20 0.54
HTT P42858 2/20 0.53
HPGD P15428 2/20 0.51
ATM Q13315 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
FFAR4 Q5NUL3 1/20 0.51
GAA P10253 1/20 0.51
ALDH1A1 P00352 1/20 0.50
MEP1B Q16820 1/20 0.49
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31514071 0.94 PKM (0.56) PKMPKLRNPC1RAB9AMAPT
SCHEMBL1020435 0.92 FFAR4 (0.54) PKMPKLRNPC1RAB9AMAPT
SCHEMBL560493 0.88 CA12 (0.54) PKMPKLRNPC1RAB9AMAPT
SCHEMBL29437166 0.88 CA12 (0.54) PKMPKLRNPC1RAB9AMAPT
SCHEMBL3726506 0.85 PKM (0.45) PKMPKLRNPC1RAB9AMAPT
SCHEMBL2878663 0.85 PKM (0.45) PKMPKLRNPC1RAB9AMAPT
SCHEMBL31248492 0.85 PKM (0.45) PKMPKLRNPC1RAB9AMAPT
SCHEMBL2224714 0.83 PKM (0.65) PKMPKLRNPC1RAB9AMAPT
SCHEMBL4611622 0.80 PKM (0.41) PKMPKLRNPC1RAB9AMAPT
SCHEMBL2986914 0.80 PKM (0.66) PKMPKLRNPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 449 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10125226-B2 Scale-up process of bifunctionalized triblock copolymers with secondary and tertiary amines, with application in dewatering and desalting of heavy crude oils INSTITUTO MEXICANO DEL PETROLEO (MX) 2018-11-13 US claimed
US-20140364566-A1 SCALE-UP PROCESS OF BIFUNCTIONALIZED TRIBLOCK COPOLYMERS WITH SECONDARY AND TERTIARY AMINES, WITH APPLICATION IN DEWATERING AND DESALTING OF HEAVY CRUDE OILS INSTITUTO MEXICANO DEL PETROLEO (MX) 2014-12-11 US claimed
EP-0583960-B1 Synthesis of bicyclic aromatic sulfonic acids, sulfonyl chlorides and sulfonamides LILLY CO ELI (US) 1997-05-21 EP claimed
US-5387681-A Reacting a bicyclic aromatic compound with a complex of sulfur trioxide-N,N-dimethylformamide; water miscible, non-reactive solvent; thionyl halide ELI LILLY AND COMPANY (US) 1995-02-07 US claimed
EP-0583960-A2 Synthesis of bicyclic aromatic sulfonic acids, sulfonyl chlorides and sulfonamides ELI LILLY AND COMPANY (US) 1994-02-23 EP claimed
EP-0254577-B1 SYNTHESIS OF BICYCLIC AROMATIC SULFONYL CHLORIDES ELI LILLY AND COMPANY (US) 1989-09-27 EP claimed
EP-0254577-A1 Synthesis of bicyclic aromatic sulfonyl chlorides ELI LILLY AND COMPANY (US) 1988-01-27 EP claimed
EP-4721737-A1 USE OF PHARMACEUTICAL COMPOSITION COMPRISING COMPOUND HAVING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE FOR TREATING ANEMIA-RELATED DISEASES Scinnohub Pharmaceutical Co., Ltd. (CN) 2026-04-08 EP disclosed
EP-4596534-A1 NONCOVALENT SMALL-MOLECULE INHIBITORS OF THE KEAP1-NRF2 INTERACTION University of Copenhagen (DK) 2025-08-06 EP disclosed
WO-2025100970-A1 TNAP INHIBITORY COMPOUND AND USE THEREOF 주식회사 레드엔비아 2025-05-15 WO disclosed
US-20250145635-A1 COMPOUND CONTAINING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE AND USE THEREOF IN MEDICINE SCINNOHUB PHARMACEUTICAL CO., LTD. (CN) 2025-05-08 US disclosed
WO-2025075722-A1 PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, AND CATALYST FOR POLYMERIZAING OLEFINS FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2025-04-10 WO disclosed
US-20250115687-A1 PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, AND CATALYST FOR POLYMERIZAING OLEFINS FORMOSA PLASTICS CORP USA (US) 2025-04-10 US disclosed
WO-1996028464-A1 BIS-AMINO ACID HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1996-09-19 WO disclosed
WO-1996028418-A1 SULFONYLALKANOYLAMINO HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1996-09-19 WO disclosed
WO-1996025934-A1 ALPHA 1a ADRENERGIC RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 1996-08-29 WO disclosed
WO-1996022287-A1 BIS-SULFONAMIDE HYDROXYETHYLAMINO RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1996-07-25 WO disclosed
WO-1995028397-A1 ALPHA1C ADRENERGIC RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 1995-10-26 WO disclosed
US-5387681-A Reacting a bicyclic aromatic compound with a complex of sulfur trioxide-N,N-dimethylformamide; water miscible, non-reactive solvent; thionyl halide ELI LILLY AND COMPANY (US) 1995-02-07 US disclosed
EP-0583960-A2 Synthesis of bicyclic aromatic sulfonic acids, sulfonyl chlorides and sulfonamides ELI LILLY AND COMPANY (US) 1994-02-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250145635-A1 COMPOUND CONTAINING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE AND USE THEREOF IN MEDICINE BCL9, USP9X, BCL9L PKM 266/4885PKLR 177/4885NPC1 1528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.