SCHEMBL7066876

SCHEMBL7066876

C[C@@H](O[Si](C)(C)C(C)(C)C)C1C(=O)NC1Sc1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CTSL P07711 2/20 0.32
CTSS P25774 2/20 0.32
CTSK P43235 2/20 0.32
DDB1 Q16531 1/20 0.30
CRBN Q96SW2 1/20 0.30
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6481304 1.00 CTSL (0.32) CTSLCTSSCTSKDDB1CRBN
SCHEMBL8653110 1.00 CTSL (0.32) CTSLCTSSCTSKDDB1CRBN
SCHEMBL6474175 1.00 CTSL (0.32) CTSLCTSSCTSKDDB1CRBN
SCHEMBL6485090 1.00 CTSL (0.32) CTSLCTSSCTSKDDB1CRBN
SCHEMBL10499505 0.88 DDB1 (0.33) DDB1CRBN
SCHEMBL9764832 0.88 DDB1 (0.33) DDB1CRBN
SCHEMBL10499943 0.87 DDB1 (0.38) DDB1CRBN
SCHEMBL6399063 0.84 CTSL (0.33) CTSLCTSSCTSK
SCHEMBL6399660 0.84 CTSL (0.33) CTSLCTSSCTSK
SCHEMBL9428785 0.83 ELANE (0.31) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0638552-B1 PROCESS FOR SYNTHESIZING 4-SUBSTITUTED AZETIDINONE DERIVATIVE DAIICHI SUNTORY PHARMA CO LTD (JP) 2003-06-04 EP claimed