SCHEMBL9764832

SCHEMBL9764832

CC(O[Si](C)(C)C(C)(C)C)C1C(=O)N[C@@H]1Sc1ccc(Cl)cc1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 1/20 0.33
CRBN Q96SW2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10499505 1.00 DDB1 (0.33) DDB1CRBN
SCHEMBL6474175 0.88 CTSL (0.32) DDB1CRBN
SCHEMBL7066876 0.88 CTSL (0.32) DDB1CRBN
SCHEMBL6485090 0.88 CTSL (0.32) DDB1CRBN
SCHEMBL6481304 0.88 CTSL (0.32) DDB1CRBN
SCHEMBL8653110 0.88 CTSL (0.32) DDB1CRBN
SCHEMBL10499943 0.87 DDB1 (0.38) DDB1CRBN
SCHEMBL9759756 0.79
SCHEMBL9759755 0.79
SCHEMBL10390381 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5026844-A Process for the preparation of 4-acyloxy-2-azetidinone derivatives SUNTORY LIMITED (JP) 1991-06-25 US disclosed