Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28655249 | 0.76 | L3MBTL1 (0.45) | SMN1; SMN2L3MBTL1AHRCHRM2KDM4E | |
| SCHEMBL21742046 | 0.76 | SMN1; SMN2 (0.39) | SMN1; SMN2L3MBTL1AHRCHRM2KDM4E | |
| SCHEMBL3299722 | 0.75 | SMN1; SMN2 (0.44) | SMN1; SMN2L3MBTL1CHRM2KDM4ERAB9A | |
| SCHEMBL21742327 | 0.74 | SMN1; SMN2 (0.37) | SMN1; SMN2L3MBTL1AHRCHRM2KDM4E | |
| SCHEMBL21742378 | 0.73 | AHR (0.39) | SMN1; SMN2L3MBTL1AHRCHRM2KDM4E | |
| SCHEMBL21742319 | 0.72 | CHRM2 (0.43) | SMN1; SMN2L3MBTL1CHRM2KDM4ERAB9A | |
| SCHEMBL4789499 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1AHRCHRM2KDM4E | |
| SCHEMBL21742149 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1AHRCHRM2KDM4E | |
| SCHEMBL21742315 | 0.72 | SMN1; SMN2 (0.38) | SMN1; SMN2L3MBTL1AHRCHRM2KDM4E | |
| SCHEMBL21742047 | 0.71 | SMN1; SMN2 (0.37) | SMN1; SMN2L3MBTL1AHRCHRM2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891988-B1 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE SPA (IT) | 2003-06-04 | — | — | EP | disclosed |
| EP-0451645-B1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC (US) | 1999-05-12 | — | — | EP | disclosed |
| EP-0891988-A2 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1999-01-20 | — | — | EP | disclosed |
| US-5068213-A | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | HINMONT INCORPORATED (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0451645-A2 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1991-10-16 | — | — | EP | disclosed |