Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.74 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.74 |
| ▸ | CDC25A | P30304 | 11/20 | 0.72 |
| ▸ | CES1 | P23141 | 3/20 | 0.72 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL281625 | 0.85 | ALDH1A1 (1.00) | ALDH1A1ALDH2ALDH3A1CDC25ACES1 | |
| SCHEMBL29821573 | 0.84 | CDC25A (1.00) | ALDH1A1ALDH2ALDH3A1CDC25ACES1 | |
| SCHEMBL12930216 | 0.84 | CDC25A (1.00) | ALDH1A1ALDH2ALDH3A1CDC25ACES1 | |
| SCHEMBL30382960 | 0.84 | CDC25A (0.77) | ALDH1A1ALDH2ALDH3A1CDC25ACES1 | |
| SCHEMBL29613389 | 0.84 | CDC25A (1.00) | ALDH1A1ALDH2ALDH3A1CDC25ACES1 | |
| SCHEMBL282035 | 0.84 | CDC25A (1.00) | ALDH1A1ALDH2ALDH3A1CDC25ACES1 | |
| SCHEMBL28299129 | 0.84 | CDC25A (1.00) | ALDH1A1ALDH2ALDH3A1CDC25ACES1 | |
| SCHEMBL3016105 | 0.84 | CDC25A (1.00) | ALDH1A1ALDH2ALDH3A1CDC25ACES1 | |
| SCHEMBL21754749 | 0.83 | ALDH1A1 (0.73) | ALDH1A1ALDH2ALDH3A1CDC25ACES1 | |
| SCHEMBL15571795 | 0.83 | ALDH1A1 (0.55) | ALDH1A1ALDH2ALDH3A1CDC25ACES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014854-A1 | 3-IMINO-2-INDOLONES FOR THE TREATMENT OF DEPRESSION AND/OR ANXIETY | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2004-02-19 | — | — | WO | disclosed |