Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.73 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.73 |
| ▸ | CDC25A | P30304 | 10/20 | 0.71 |
| ▸ | CES1 | P23141 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3019788 | 0.89 | ALDH1A1 (0.90) | ALDH1A1ALDH2ALDH3A1CDC25ACES1 | |
| SCHEMBL19297268 | 0.89 | ALDH1A1 (0.62) | ALDH1A1ALDH2ALDH3A1CDC25ACES1 | |
| SCHEMBL29511230 | 0.86 | CHRM2 (0.61) | ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL149620 | 0.86 | CHRM2 (0.61) | ALDH1A1ALDH2ALDH3A1 | |
| Hydrochloric Acid SCHEMBL10957581 | 0.85 | CHRM2 (0.59) | ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL281625 | 0.84 | ALDH1A1 (1.00) | ALDH1A1ALDH2ALDH3A1CDC25ACES1 | |
| SCHEMBL282035 | 0.83 | CDC25A (1.00) | ALDH1A1ALDH2ALDH3A1CDC25ACES1 | |
| SCHEMBL3016105 | 0.83 | CDC25A (1.00) | ALDH1A1ALDH2ALDH3A1CDC25ACES1 | |
| SCHEMBL7067149 | 0.83 | ALDH1A1 (0.74) | ALDH1A1ALDH2ALDH3A1CDC25ACES1 | |
| SCHEMBL30382960 | 0.83 | CDC25A (0.77) | ALDH1A1ALDH2ALDH3A1CDC25ACES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10570148-B2 | N-alkyl-2-phenoxyethanamines, their preparation and use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570148-B2 | N-alkyl-2-phenoxyethanamines, their preparation and use | HRH3, CBR3, KCNH3 | ALDH1A1 2874/4885ALDH2 3181/4885ALDH3A1 1123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.