Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 6/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 5/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7518556 | 1.00 | KLK7 (0.36) | KLK7KDM1AABCB1GPR119KLK5 | |
| SCHEMBL7067383 | 0.77 | KLK7 (0.36) | KLK7ABCB1GPR119KLK5USP30 | |
| SCHEMBL7515491 | 0.77 | KLK7 (0.36) | KLK7ABCB1GPR119KLK5USP30 | |
| SCHEMBL7067178 | 0.73 | GPR119 (0.34) | KLK7KDM1AABCB1GPR119KLK5 | |
| SCHEMBL7518553 | 0.73 | GPR119 (0.34) | KLK7KDM1AABCB1GPR119KLK5 | |
| SCHEMBL5150314 | 0.69 | ABCB1 (0.37) | KDM1AABCB1GPR119USP30RORC | |
| SCHEMBL30811272 | 0.67 | MEN1 (0.38) | KLK7ABCB1GPR119RORCKDM4E | |
| SCHEMBL5172836 | 0.67 | TSHR (0.35) | KDM1AABCB1GPR119USP30RORC | |
| SCHEMBL10518514 | 0.65 | KDM1A (0.31) | KDM1A | |
| SCHEMBL8592564 | 0.65 | KLK7 (0.38) | KLK7ABCB1KLK5PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1314041-A2 | SCREEN FOR GLUTAMATE REUPTAKE INHIBITORS, STIMULATORS, AND MODULATORS | Annovis, Inc. (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018941-A2 | SCREEN FOR GLUTAMATE REUPTAKE INHIBITORS, STIMULATORS, AND MODULATORS | ANNOVIS, INC. (US) | 2002-03-07 | — | — | WO | disclosed |