Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | KLK7 | P49862 | 2/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 8/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7518553 | 1.00 | GPR119 (0.34) | GPR119KLK7USP30RORCKDM1A | |
| SCHEMBL7067385 | 0.73 | GPR119 (0.36) | GPR119KLK7RORCKLK5STS | |
| SCHEMBL7515485 | 0.73 | GPR119 (0.36) | GPR119KLK7RORCKLK5STS | |
| SCHEMBL7518556 | 0.73 | KLK7 (0.36) | GPR119KLK7USP30RORCKDM1A | |
| SCHEMBL7067183 | 0.73 | KLK7 (0.36) | GPR119KLK7USP30RORCKDM1A | |
| SCHEMBL7067952 | 0.70 | USP30 (0.33) | GPR119USP30RORCKDM1A | |
| SCHEMBL31165320 | 0.65 | RIPK1 (0.42) | GPR119RORCABCB1 | |
| SCHEMBL4555170 | 0.64 | GPR119 (0.37) | GPR119KLK7USP30RORCKLK5 | |
| SCHEMBL13108777 | 0.63 | NOTUM (0.48) | GPR119KDM1A | |
| SCHEMBL7067547 | 0.63 | KDM1A (0.34) | GPR119RORCKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1314041-A2 | SCREEN FOR GLUTAMATE REUPTAKE INHIBITORS, STIMULATORS, AND MODULATORS | Annovis, Inc. (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018941-A2 | SCREEN FOR GLUTAMATE REUPTAKE INHIBITORS, STIMULATORS, AND MODULATORS | ANNOVIS, INC. (US) | 2002-03-07 | — | — | WO | disclosed |