Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.53 |
| ▸ | SLC10A6 | Q3KNW5 | 2/20 | 0.47 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.47 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 3/20 | 0.41 |
| ▸ | FLT4 | P35916 | 3/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.41 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067188 | 1.00 | METAP2 (0.53) | METAP2SLC10A6SLC10A2SLC10A1MEN1 | |
| SCHEMBL7062731 | 0.90 | METAP2 (0.44) | METAP2SLC10A6SLC10A2SLC10A1KMT2A | |
| SCHEMBL7062734 | 0.90 | METAP2 (0.44) | METAP2SLC10A6SLC10A2SLC10A1KMT2A | |
| SCHEMBL7066753 | 0.82 | KCNK2 (0.47) | METAP2SLC10A6MEN1KMT2AAKR1C2 | |
| SCHEMBL7066756 | 0.82 | KCNK2 (0.47) | METAP2SLC10A6MEN1KMT2AAKR1C2 | |
| SCHEMBL6346651 | 0.81 | METAP2 (0.65) | METAP2SLC10A6SLC10A2SLC10A1MEN1 | |
| SCHEMBL6356961 | 0.80 | METAP2 (0.53) | METAP2SLC10A6SLC10A2SLC10A1MEN1 | |
| SCHEMBL6347755 | 0.73 | MIF (0.54) | METAP2SLC10A6SLC10A2SLC10A1MEN1 | |
| SCHEMBL6351726 | 0.72 | MAPT (0.50) | METAP2KMT2ADNMT3ATP53 | |
| SCHEMBL1307201 | 0.72 | KCNK2 (0.64) | METAP2MEN1KMT2AAKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |