Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK2 | O95069 | 1/20 | 0.47 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | RPA1 | P27694 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.43 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066756 | 1.00 | KCNK2 (0.47) | KCNK2KCNK10MAPTAKR1C2AKR1C1 | |
| SCHEMBL7067188 | 0.82 | METAP2 (0.53) | AKR1C2AKR1C1AKR1C4AKR1C3METAP2 | |
| SCHEMBL7067191 | 0.82 | METAP2 (0.53) | AKR1C2AKR1C1AKR1C4AKR1C3METAP2 | |
| SCHEMBL6353396 | 0.81 | RPA1 (0.58) | KCNK2KCNK10MAPTMETAP2RPA1 | |
| SCHEMBL1308635 | 0.79 | AKR1C2 (0.65) | KCNK2KCNK10MAPTAKR1C2AKR1C1 | |
| SCHEMBL7062731 | 0.79 | METAP2 (0.44) | KCNK2KCNK10MAPTAKR1C2AKR1C1 | |
| SCHEMBL7062734 | 0.79 | METAP2 (0.44) | KCNK2KCNK10MAPTAKR1C2AKR1C1 | |
| SCHEMBL6349927 | 0.77 | MAPT (0.63) | KCNK2KCNK10MAPTAKR1C2AKR1C1 | |
| SCHEMBL6349921 | 0.77 | MAPT (0.63) | KCNK2KCNK10MAPTAKR1C2AKR1C1 | |
| SCHEMBL17166275 | 0.75 | AKR1C2 (0.73) | KCNK2KCNK10MAPTAKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |