Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 7/20 | 0.45 |
| ▸ | CD74 | P04233 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7069590 | 0.86 | MIF (0.46) | MIFCD74NPC1ALDH1A1IDO1 | |
| SCHEMBL7067342 | 0.76 | IDO1 (0.55) | MIFCD74NPC1IDO1MEN1 | |
| SCHEMBL7597100 | 0.71 | ALDH1A1 (0.56) | NPC1ALDH1A1HPGDNPSR1MEN1 | |
| SCHEMBL17886629 | 0.69 | MIF (0.64) | MIFCD74NPC1IDO1MEN1 | |
| SCHEMBL18171790 | 0.69 | IDO1 (0.79) | MIFCD74NPC1IDO1MEN1 | |
| SCHEMBL30806471 | 0.69 | IDO1 (0.64) | MIFCD74NPC1ALDH1A1IDO1 | |
| SCHEMBL24346159 | 0.68 | HTR6 (0.54) | NPC1ALDH1A1HPGDNPSR1MEN1 | |
| SCHEMBL16565537 | 0.68 | MIF (0.76) | MIFCD74MEN1KMT2APOLB | |
| SCHEMBL31451497 | 0.67 | KMT2A (0.61) | MIFCD74ALDH1A1IDO1KMT2A | |
| SCHEMBL10825112 | 0.66 | PDE7A (0.68) | ALDH1A1HPGDNPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1316550-A1 | 6-Acylamino-5-substituted-benzoxazol-2-one compounds and method for using them | EASTMAN KODAK COMPANY (US) | 2003-06-04 | — | — | EP | disclosed |
| US-6515176-B1 | Disclosed is a 6-acylamino-5-substituted-benzoxazol-2-one compound having the structural formula I: Also disclosed is a method for forming a cyan dye-forming coupler from the above compound. The method and intermediate with a simplified | EASTMAN KODAK COMPANY | 2003-02-04 | — | — | US | disclosed |