Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL7069915 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TSHRCYP3A4ALOX15HIF1A | |
| Chloroform SCHEMBL3805497 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TSHRCYP3A4ALOX15HIF1A | |
| Chloroform SCHEMBL2457679 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TSHRCYP3A4ALOX15HIF1A | |
| Chloroform SCHEMBL2454480 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TSHRCYP3A4ALOX15HIF1A | |
| Chloroform SCHEMBL7067406 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TSHRCYP3A4ALOX15HIF1A | |
| Chloroform SCHEMBL7067628 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TSHRCYP3A4ALOX15HIF1A | |
| Chloroform SCHEMBL2455514 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TSHRCYP3A4ALOX15HIF1A | |
| Chloroform SCHEMBL7066821 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TSHRCYP3A4ALOX15HIF1A | |
| Chloroform SCHEMBL15163618 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TSHRCYP3A4ALOX15HIF1A | |
| Chloroform SCHEMBL7070638 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TSHRCYP3A4ALOX15HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163675-A | Nitrogen-containing heterocyclic compound | KYOWA HAKKO KOGYO KK (JP) | 2008-04-16 | — | — | CN | disclosed |
| US-6518268-B1 | Telomerase inhibitors and methods of their use | GERON CORPORATION | 2003-02-11 | — | — | US | disclosed |
| CN-1321153-A | telomerase inhibitors and methods of use thereof | GERON CORP (US) | 2001-11-07 | — | — | CN | disclosed |
| WO-2001002377-A9 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORP (US) | 2001-10-11 | — | — | WO | disclosed |
| EP-1109796-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | Geron Corporation (US) | 2001-06-27 | — | — | EP | disclosed |
| WO-2001002377-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORPORATION (US) | 2001-01-11 | — | — | WO | disclosed |