Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL7069915 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TSHRCYP3A4ALOX15HIF1A | |
| Chloroform SCHEMBL3805497 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TSHRCYP3A4ALOX15HIF1A | |
| Chloroform SCHEMBL2457679 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TSHRCYP3A4ALOX15HIF1A | |
| Chloroform SCHEMBL7067406 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TSHRCYP3A4ALOX15HIF1A | |
| Chloroform SCHEMBL7067628 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TSHRCYP3A4ALOX15HIF1A | |
| Chloroform SCHEMBL2455514 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TSHRCYP3A4ALOX15HIF1A | |
| Chloroform SCHEMBL7066821 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TSHRCYP3A4ALOX15HIF1A | |
| Chloroform SCHEMBL15163618 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TSHRCYP3A4ALOX15HIF1A | |
| Chloroform SCHEMBL7070638 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TSHRCYP3A4ALOX15HIF1A | |
| Chloroform SCHEMBL7067332 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TSHRCYP3A4ALOX15HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673908-B2 | Kynurenine production inhibitor | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2014-03-18 | — | — | US | disclosed |
| EP-2374802-A1 | KYNURENINE PRODUCTION INHIBITOR | Kyowa Hakko Kirin Co., Ltd. (JP) | 2011-10-12 | — | — | EP | disclosed |
| US-20110237584-A1 | KYNURENINE PRODUCTION INHIBITOR | KYOWA KIRIN CO., LTD. (JP) | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237584-A1 | KYNURENINE PRODUCTION INHIBITOR | KYNU, KMO, IDO1 | ALDH1A1 1689/4885TSHR 1897/4885CYP3A4 110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.