Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.59 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.59 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.59 |
| ▸ | TNKS | O95271 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10348520 | 1.00 | HAO1 (0.75) | HAO1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL3439644 | 0.94 | HAO1 (0.84) | HAO1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL316674 | 0.94 | HAO1 (0.84) | HAO1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL9113928 | 0.90 | HAO1 (0.68) | HAO1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL9113934 | 0.90 | HAO1 (0.68) | HAO1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL243735 | 0.88 | HAO1 (0.75) | HAO1ALDH1A1MAPTKMT2AKDM4E | |
| Dimethylamine SCHEMBL14875132 | 0.88 | HAO1 (0.75) | HAO1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL15300315 | 0.86 | HAO1 (1.00) | HAO1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL15300314 | 0.86 | HAO1 (1.00) | HAO1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL7264356 | 0.85 | PAM (0.56) | HAO1ALDH1A1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240398-B1 | DISSYMMETRICAL 1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLIC-ACID DERIVATIVES, PREPARATION PROCESSES AND THERAPEUTICAL USE | FOURNIER INNOVATION ET SYNERGIE (FR) | 1991-05-15 | — | — | EP | claimed |
| EP-0239105-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING 5-PHENYL-1,3-DIOXOALKENYL COMPOUNDS | G.D. Searle & Co. (US) | 1990-05-23 | — | — | EP | claimed |
| EP-0197488-A2 | 1,4-Dihydropyiridine derivative, a process for preparing the same, a pharmaceutical composition as well as the use thereof | Eisai Co., Ltd. (JP) | 1986-10-15 | — | — | EP | claimed |
| CN-110664792-B | Composition for spinal fusion compounding and preparation method and application thereof | 北京和理咨询有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-110664792-B | Composition for spinal fusion compounding and preparation method and application thereof | 北京和理咨询有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-110664792-A | Composition for spinal fusion compounding and preparation method and application thereof | 北京和理咨询有限公司 | 2020-01-10 | — | — | CN | disclosed |
| CN-110664792-A | Composition for spinal fusion compounding and preparation method and application thereof | 北京和理咨询有限公司 | 2020-01-10 | — | — | CN | disclosed |
| EP-1189958-B1 | TRIFUNCTIONAL OLEFINIC-CAPPED POLYMERS AND COMPOSITIONS THAT INCLUDE SUCH POLYMERS | LORD CORP (US) | 2003-08-27 | — | — | EP | disclosed |
| US-6562910-B2 | Polymer having end group or pendant functional group capped with a benzylidenecyanoacetate group; reacting hydroxy-terminated polybutadiene with methyl benzylidenecyanoacetate; curable mixtures; adhesives | LORD CORPORATION | 2003-05-13 | — | — | US | disclosed |
| US-6562181-B2 | Bonding together two substrates by applying to a first substrate formulation of mixture of trifunctional olefinic monomer, olefinic second monomer that is copolymerizable and free radical initiator; contacting second substrate | LORD CORPORATION | 2003-05-13 | — | — | US | disclosed |
| US-20030032732-A1 | Trifunctional olefinic-capped polymers and compositions that include such polymers | F RIGHETTINI ROBIN (US) | 2003-02-13 | — | — | US | disclosed |
| EP-0197488-A2 | 1,4-Dihydropyiridine derivative, a process for preparing the same, a pharmaceutical composition as well as the use thereof | Eisai Co., Ltd. (JP) | 1986-10-15 | — | — | EP | disclosed |
| US-4446325-A | VASODILATION, HYPOTENSIVE AGENTS | MARUKO SEIYAKU CO., LTD. (JP) | 1984-05-01 | — | — | US | disclosed |
| US-4419518-A | VASODILATION, HYPOTENSIVE AGENTS | TOKYO TANABE CO. L.T.D. (JP) | 1983-12-06 | — | — | US | disclosed |
| US-4418197-A | VASODILATORS, HYPOTENSIVE AGENTS | TOKYO TANABE COMPANY, LIMITED (JP) | 1983-11-29 | — | — | US | disclosed |
| US-4261988-A | ANTICHOLESTEROL AGENTS USED IN ANIMAL HUSBANDRY | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-14 | — | — | US | disclosed |
| US-4038399-A | 1,4-DIHYDROPYRIDINE CARBOXYLIC ACID ESTERS USEFUL AS CORONARY VESSEL DILATORS AND ANTI-HYPERTENSIVES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-26 | — | — | US | disclosed |
| US-4031104-A | ANTIHYPERTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-21 | — | — | US | disclosed |
| US-3996234-A | CORONARY VESSEL DILATORS, HYPOTENSIVES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-07 | — | — | US | disclosed |
| US-3974275-A | 1,4-Dihydropyridine carboxylic acid esters useful as coronary vessel dilators and anti-hypertensives | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-10 | — | — | US | disclosed |