Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.67 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.67 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | RECQL | P46063 | 2/20 | 0.67 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.67 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.67 |
| ▸ | TNKS | O95271 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3439644 | 1.00 | HAO1 (0.84) | HAO1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL7067334 | 0.94 | HAO1 (0.75) | HAO1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL10348520 | 0.94 | HAO1 (0.75) | HAO1ALDH1A1MAPTKMT2AKDM4E | |
| Dimethylamine SCHEMBL14875132 | 0.94 | HAO1 (0.75) | HAO1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL243735 | 0.94 | HAO1 (0.75) | HAO1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL15300315 | 0.92 | HAO1 (1.00) | HAO1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL15300314 | 0.92 | HAO1 (1.00) | HAO1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL1650908 | 0.90 | HAO1 (0.70) | HAO1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL11377652 | 0.90 | HAO1 (0.70) | HAO1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL1650906 | 0.90 | HAO1 (0.70) | HAO1ALDH1A1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130102498-A1 | COMPOSITIONS AND METHODS FOR DETECTING AMYLOID-BETA-DEGRADING ENZYME ACTIVITY | ACADEMIA SINICA (TW) | 2013-04-25 | — | — | US | claimed |
| EP-0239105-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING 5-PHENYL-1,3-DIOXOALKENYL COMPOUNDS | G.D. Searle & Co. (US) | 1990-05-23 | — | — | EP | claimed |
| US-4761503-A | LEUKOTRIENE BIOSYNTHESIS INHIBITORS CONDENSATION OF BENZALDEHYDE WITH ACETOACETATE COMPOUND | G. D. SEARLE & CO. (US) | 1988-08-02 | — | — | US | claimed |
| EP-0239105-A2 | Pharmaceutical compositions containing 5-phenyl-1,3-dioxoalkenyl compounds | G.D. Searle & Co. (US) | 1987-09-30 | — | — | EP | claimed |
| US-4649157-A | ANTIALLERGENS, ANTIINFLAMMATORY | G. D. SEARLE & CO. (US) | 1987-03-10 | — | — | US | claimed |
| EP-4717762-A1 | CURCUMIN PRODUCING GRAM POSITIVE BACTERIA | Universität des Saarlandes, eine Körperschaft des Öffentlichen Rechts (DE) | 2026-04-01 | — | — | EP | disclosed |
| US-11026897-B2 | Composition of curcumagalactomannoside and hops extract | METAGENICS, INC. (US) | 2021-06-08 | — | — | US | disclosed |
| US-20200046651-A1 | METHOD OF TREATING INFLAMMATORY BOWEL DISEASE | WHITEHORSE CAPITAL ORIGINATION, LLC, AS AGENT | 2020-02-13 | — | — | US | disclosed |
| WO-2020033796-A1 | METHOD OF TREATING INFLAMMATORY BOWEL DISEASE | METAGENICS, INC. (US) | 2020-02-13 | — | — | WO | disclosed |
| US-20160039734-A1 | THERAPEUTIC CURCUMIN DERIVATIVES | STC UNM (US) | 2016-02-11 | — | — | US | disclosed |
| US-9233263-B2 | Photoprotector and/or photoimmunoprotector compositions of the skin and their uses | INDUSTRIAL FARMACEUTICA CANTABRIA, S.A. (ES) | 2016-01-12 | — | — | US | disclosed |
| US-9187397-B2 | Therapeutic curcumin derivatives | STC.UNM (US) | 2015-11-17 | — | — | US | disclosed |
| WO-2003035007-A2 | CURCUMINOID COMPOSITIONS EXHIBITING SYNERGISTIC INHIBITION OF THE EXPRESSION AND/OR ACTIVITY OF CYCLOOXYGENASE-2 | METAPROTEOMICS, LLC (US) | 2003-05-01 | — | — | WO | disclosed |
| WO-2003007975-A1 | CURCUMINOID COMPOSITIONS EXHIBITING SYNERGISTIC INHIBITION OF THE EXPRESSION AND/OR ACTIVITY OF CYCLOOXYGENASE-2 | METAPROTEOMICS, LLC (US) | 2003-01-30 | — | — | WO | disclosed |
| EP-0210284-B1 | 1,3-DITHIOL-2-YLIDENE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-08-19 | — | — | EP | disclosed |
| US-4761503-A | LEUKOTRIENE BIOSYNTHESIS INHIBITORS CONDENSATION OF BENZALDEHYDE WITH ACETOACETATE COMPOUND | G. D. SEARLE & CO. (US) | 1988-08-02 | — | — | US | disclosed |
| EP-0239105-A2 | Pharmaceutical compositions containing 5-phenyl-1,3-dioxoalkenyl compounds | G.D. Searle & Co. (US) | 1987-09-30 | — | — | EP | disclosed |
| US-4668799-A | Anti-hepatitis and anti-cirrhotic 1,3-dithiol-2-ylidene derivatives, and pharmaceutical compositions therefor | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1987-05-26 | — | — | US | disclosed |
| US-4649157-A | ANTIALLERGENS, ANTIINFLAMMATORY | G. D. SEARLE & CO. (US) | 1987-03-10 | — | — | US | disclosed |
| EP-0210284-A1 | 1,3-Dithiol-2-ylidene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1987-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039734-A1 | THERAPEUTIC CURCUMIN DERIVATIVES | FABP2, GLS2, FABP1 | HAO1 3822/4885ALDH1A1 670/4885MAPT 448/4885 |
| US-11026897-B2 | Composition of curcumagalactomannoside and hops extract | HMGB1, CHIT1, NOD2 | HAO1 1816/4885ALDH1A1 4598/4885MAPT 1152/4885 |
| US-20200046651-A1 | METHOD OF TREATING INFLAMMATORY BOWEL DISEASE | NOD2, NLRP1, NOD1 | HAO1 1452/4885ALDH1A1 4630/4885MAPT 1167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.