SCHEMBL5355271

SCHEMBL5355271

Nc1nccc(O)c1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
GABRP O00591 3/20 0.42
GABRD O14764 3/20 0.42
GABRA1 P14867 3/20 0.42
GABRB1 P18505 3/20 0.42
GABRG2 P18507 3/20 0.42
GABRB3 P28472 3/20 0.42
GABRA5 P31644 3/20 0.42
GABRA3 P34903 3/20 0.42
GABRA2 P47869 3/20 0.42
GABRB2 P47870 3/20 0.42
GABRA4 P48169 3/20 0.42
GABRE P78334 3/20 0.42
GABRA6 Q16445 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22688908 0.81 NAPRT (0.48) NAPRTGABRPGABRDGABRA1GABRB1
SCHEMBL19857454 0.79 NAPRT (0.57) NAPRTGABRPGABRDGABRA1GABRB1
SCHEMBL7067358 0.78 CA12 (0.50) NAPRTCA12CA1CA2CA7
SCHEMBL1260539 0.78 NOS2 (0.52) NAPRTGABRPGABRDGABRA1GABRB1
SCHEMBL3426148 0.78 NAPRT (0.46) NAPRTGABRPGABRDGABRA1GABRB1
SCHEMBL11819966 0.78 NAPRT (0.46) NAPRTGABRPGABRDGABRA1GABRB1
SCHEMBL5249643 0.78 NAPRT (0.46) NAPRTGABRPGABRDGABRA1GABRB1
SCHEMBL11895139 0.78 NAPRT (0.46) NAPRTGABRPGABRDGABRA1GABRB1
SCHEMBL1002512 0.77 KDM4E (0.52) NAPRTCA12CA1CA2CA7
Hydrochloric Acid SCHEMBL15880101 0.76 NAPRT (0.44) NAPRTGABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5430049-A Treating hyperproliferative disorders GAUT ZANE N (US) 1995-07-04 US claimed
US-5118937-A Process and device for the laser desorption of an analyte molecular ions, especially of biomolecules FINNIGAN MAT GMBH (DE) 1992-06-02 US claimed
US-20070015900-A1 Aromatic amide polymer systems and methods for making the same FOWKES STEVEN W 2007-01-18 US disclosed
US-20070015900-A1 Aromatic amide polymer systems and methods for making the same FOWKES STEVEN W 2007-01-18 US disclosed
US-7160978-B2 Aromatic amide polymer systems and methods for making the same FOWKES STEVEN W 2007-01-09 US disclosed
US-7160978-B2 Aromatic amide polymer systems and methods for making the same FOWKES STEVEN W 2007-01-09 US disclosed
US-20040171756-A1 Aromatic amide polymer systems and methods for making the same FOWKES STEVEN W (US) 2004-09-02 US disclosed
US-5430049-A Treating hyperproliferative disorders GAUT ZANE N (US) 1995-07-04 US disclosed
US-3965100-A 2,3-Dihydrocyclopenta[d]pyrido[1,2-a]pyrimidin-10(1H)-one and its derivatives E. R. SQUIBB & SONS, INC. (US) 1976-06-22 US disclosed