Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA3 | P07451 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL227238 | 0.79 | SMN1; SMN2 (0.59) | AKR1C3AKR1C2KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL6359832 | 0.74 | MAPT (0.57) | AKR1C3AKR1C2POLBCA1CA2 | |
| SCHEMBL22720157 | 0.72 | AKR1C3 (0.62) | AKR1C3AKR1C2KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL23457081 | 0.70 | RAB9A (0.58) | KDM4EPOLBSMN1; SMN2HSD17B10HPGD | |
| SCHEMBL1180221 | 0.70 | LCK (0.58) | AKR1C3AKR1C2KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL31682610 | 0.70 | RAB9A (0.58) | KDM4EPOLBSMN1; SMN2HSD17B10HPGD | |
| SCHEMBL570906 | 0.70 | KDM4E (0.63) | AKR1C3AKR1C2KDM4EPOLBHSD17B10 | |
| SCHEMBL1652968 | 0.69 | ALDH1A1 (0.59) | KDM4EPOLBSMN1; SMN2HPGDPKM | |
| SCHEMBL571110 | 0.69 | POLB (0.72) | AKR1C3AKR1C2KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL29853731 | 0.69 | KDM4E (0.61) | AKR1C3AKR1C2KDM4EPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |