Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 16/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823389 | 0.93 | SLC6A9 (0.76) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL6828527 | 0.91 | SLC6A9 (0.69) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL7212952 | 0.91 | SLC6A9 (0.74) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL6826588 | 0.88 | SLC6A9 (0.84) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL6826463 | 0.88 | SLC6A9 (0.67) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL6823003 | 0.88 | SLC6A9 (0.64) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL6828540 | 0.88 | SLC6A9 (0.67) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL6826420 | 0.87 | SLC6A9 (0.72) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL6924044 | 0.87 | SLC6A9 (0.69) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL7229752 | 0.86 | SLC6A9 (0.57) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294677-B1 | BENZOPHENONES AND SULFONES AS INHIBITORS OF GLYCINE UPTAKE | PFIZER PROD INC (US) | 2004-11-03 | — | — | EP | disclosed |
| EP-1294677-A1 | BENZOPHENONES AND SULFONES AS INHIBITORS OF GLYCINE UPTAKE | Pfizer Products Inc. (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000602-A1 | BENZOPHENONES AND SULFONES AS INHIBITORS OF GLYCINE UPTAKE | PFIZER PRODUCTS INC. (US) | 2002-01-03 | — | — | WO | disclosed |