Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 20/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212952 | 0.87 | SLC6A9 (0.74) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL7067553 | 0.86 | SLC6A9 (0.65) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL6826355 | 0.86 | SLC6A9 (0.59) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL7212981 | 0.85 | SLC6A9 (0.58) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL6826578 | 0.85 | SLC6A9 (0.61) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL6826318 | 0.85 | SLC6A9 (0.61) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL6828527 | 0.85 | SLC6A9 (0.69) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL6826591 | 0.84 | SLC6A9 (0.55) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL6828540 | 0.84 | SLC6A9 (0.67) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL6826278 | 0.82 | UTS2R (0.53) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6506780-B2 | Benzophenones and sulfones as inhibitors of glycine uptake | PFIZER INC. | 2003-01-14 | — | — | US | disclosed |