Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.46 |
| ▸ | MTOR | P42345 | 8/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4464429 | 0.90 | PIK3CA (0.52) | PIK3CAMTORPIK3CGKDM4EMEN1 | |
| SCHEMBL7069390 | 0.83 | EPHX2 (0.49) | KDM4EMAPTALDH1A1CLK2GSK3A | |
| SCHEMBL4456006 | 0.80 | MAPK1 (0.42) | PIK3CAMTORPIK3CGKDM4EMEN1 | |
| SCHEMBL7189256 | 0.80 | RAF1 (0.54) | KDM4ECLK2GSK3AGSK3BCSNK2A1 | |
| SCHEMBL7064948 | 0.79 | KDM4E (0.45) | PIK3CAMTORPIK3CGKDM4EMEN1 | |
| SCHEMBL6257285 | 0.79 | MTOR (0.41) | PIK3CAMTORPIK3CGKDM4EMEN1 | |
| SCHEMBL5462710 | 0.78 | PIK3CA (0.40) | PIK3CAMTORPIK3CGKDM4EMEN1 | |
| SCHEMBL7070212 | 0.77 | MAPK14 (0.49) | PIK3CAKDM4EMEN1USP2KMT2A | |
| SCHEMBL28747223 | 0.75 | CLK2 (0.49) | KDM4EMEN1USP2KMT2ACLK2 | |
| SCHEMBL27559838 | 0.75 | MAPK14 (0.54) | KDM4EKMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030220336-A1 | Method of treating mucus hypersecretion | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220336-A1 | Method of treating mucus hypersecretion | MUC1, CFTR, MAPKAPK5 | CNR1 776/4885PIK3CA 368/4885MTOR 1204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.