Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10596863 | 0.83 | HSP90AA1 (0.44) | MAPK1MEN1KMT2ALTA4H | |
| SCHEMBL14269138 | 0.78 | MAPK1 (0.44) | MAPK1KCNN4ALOX15TAAR1ALDH1A1 | |
| SCHEMBL7066960 | 0.78 | TSHR (0.44) | MAPK1TSHRKCNN4ALOX15CYP1A2 | |
| SCHEMBL7069369 | 0.78 | TSHR (0.39) | MAPK1TSHRKCNN4CYP1A2ALDH1A1 | |
| SCHEMBL11497301 | 0.77 | MAPK1 (0.48) | MAPK1KCNN4ALOX15TAAR1ALDH1A1 | |
| SCHEMBL8911590 | 0.75 | CYP1A2 (0.47) | MAPK1TSHRKCNN4ALOX15CYP1A2 | |
| SCHEMBL662471 | 0.75 | SMN1; SMN2 (0.44) | MAPK1ALOX15CYP1A2ALDH1A1MEN1 | |
| SCHEMBL11065318 | 0.75 | MAPK1 (0.41) | MAPK1KCNN4ALOX15CYP1A2TAAR1 | |
| SCHEMBL28366627 | 0.75 | TSHR (0.50) | MAPK1TSHRKCNN4ALOX15CYP1A2 | |
| SCHEMBL7069034 | 0.74 | ALOX15 (0.35) | MAPK1TSHRKCNN4ALOX15KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891988-B1 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE SPA (IT) | 2003-06-04 | — | — | EP | disclosed |
| EP-0451645-B1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC (US) | 1999-05-12 | — | — | EP | disclosed |
| EP-0891988-A2 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1999-01-20 | — | — | EP | disclosed |
| US-5068213-A | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | HINMONT INCORPORATED (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0451645-A2 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1991-10-16 | — | — | EP | disclosed |