Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7069369 | 0.91 | TSHR (0.39) | TSHRMAPK1KCNN4KIF11 | |
| SCHEMBL7066960 | 0.86 | TSHR (0.44) | ALOX15TSHRMAPK1KCNN4KIF11 | |
| SCHEMBL7067742 | 0.74 | MAPK1 (0.41) | ALOX15TSHRMAPK1KCNN4KIF11 | |
| SCHEMBL7068616 | 0.69 | MEN1 (0.41) | TSHRMAPK1 | |
| SCHEMBL29044270 | 0.67 | TSHR (0.41) | ALOX15TSHRMAPK1KCNN4 | |
| SCHEMBL5145480 | 0.66 | TAAR1 (0.47) | ALOX15TSHRMAPK1KCNN4KIF11 | |
| SCHEMBL235054 | 0.65 | MAPK1 (0.42) | ALOX15TSHRMAPK1KCNN4KIF11 | |
| SCHEMBL5972484 | 0.65 | KIF11 (0.43) | ALOX15MAPK1KCNN4KIF11 | |
| SCHEMBL7066085 | 0.65 | MAPK1 (0.42) | ALOX15TSHRMAPK1KCNN4KIF11 | |
| SCHEMBL11495008 | 0.65 | TACR1 (0.51) | ALOX15MAPK1KCNN4KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891988-B1 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE SPA (IT) | 2003-06-04 | — | — | EP | disclosed |
| EP-0451645-B1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC (US) | 1999-05-12 | — | — | EP | disclosed |
| EP-0891988-A2 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1999-01-20 | — | — | EP | disclosed |
| US-5068213-A | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | HINMONT INCORPORATED (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0451645-A2 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1991-10-16 | — | — | EP | disclosed |