⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812659 | 0.86 | MMP8 (0.31) | — | |
| SCHEMBL13519403 | 0.82 | — | — | |
| SCHEMBL13519386 | 0.78 | — | — | |
| SCHEMBL7069423 | 0.77 | MAPK1 (0.31) | — | |
| SCHEMBL1563425 | 0.77 | — | — | |
| SCHEMBL13519459 | 0.75 | — | — | |
| SCHEMBL13519464 | 0.74 | OPRM1 (0.31) | — | |
| SCHEMBL5078216 | 0.74 | — | — | |
| SCHEMBL19155934 | 0.74 | — | — | |
| SCHEMBL7070383 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891988-B1 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE SPA (IT) | 2003-06-04 | — | — | EP | disclosed |
| EP-0451645-B1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC (US) | 1999-05-12 | — | — | EP | disclosed |
| EP-0891988-A2 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1999-01-20 | — | — | EP | disclosed |
| US-5068213-A | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | HINMONT INCORPORATED (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0451645-A2 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1991-10-16 | — | — | EP | disclosed |