Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAA50 | Q9GZZ1 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.34 |
| ▸ | FAP | Q12884 | 3/20 | 0.34 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.34 |
| ▸ | NMUR2 | Q9GZQ4 | 4/20 | 0.34 |
| ▸ | NMUR1 | Q9HB89 | 4/20 | 0.34 |
| ▸ | PREP | P48147 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067786 | 1.00 | NAA50 (0.35) | NAA50PTGS1GSTK1OPRM1OPRD1 | |
| SCHEMBL29936781 | 0.87 | KMT2A (0.37) | PTGS1FAPBDKRB2PREPDPP4 | |
| SCHEMBL29832674 | 0.86 | XIAP (0.37) | NAA50OPRM1FAPPREPDPP4 | |
| SCHEMBL29832543 | 0.84 | CALCRL (0.36) | NAA50OPRM1OPRD1FAPPREP | |
| SCHEMBL29411125 | 0.81 | ACE (0.43) | PTGS1FAPPREPDPP4 | |
| SCHEMBL6806059 | 0.81 | PTGS1 (0.46) | PTGS1GSTK1OPRM1OPRD1FAP | |
| SCHEMBL6806049 | 0.81 | PTGS1 (0.46) | PTGS1GSTK1OPRM1OPRD1FAP | |
| SCHEMBL29824941 | 0.80 | NTMT1 (0.45) | OPRM1OPRD1FAP | |
| SCHEMBL26389253 | 0.80 | DPP4 (0.40) | OPRM1FAPPREPDPP4 | |
| SCHEMBL29414077 | 0.80 | ITGB1 (0.35) | FAPPREPDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003055448-A2 | ANTIFUNGAL COMPOSITIONS | ACHILLION PHARMACEUTICALS, INC. (US) | 2003-07-10 | — | — | WO | disclosed |