SCHEMBL706787

SCHEMBL706787

CCCCCc1cc(O)cc(O)c1C/C=C(\C)CCC=C(C)C

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 0.71
CNR1 P21554 2/20 0.71
CNR2 P34972 2/20 0.71
TRPV1 Q8NER1 2/20 0.71
SLC6A3 Q01959 2/20 0.71
TRPA1 O75762 1/20 0.71
INHA P05111 1/20 0.71
SLC6A2 P23975 1/20 0.71
HTR2A P28223 1/20 0.71
SLC6A4 P31645 1/20 0.71
OPRM1 P35372 1/20 0.71
KCNH2 Q12809 1/20 0.71
TRPM8 Q7Z2W7 1/20 0.71
TRPV3 Q8NET8 1/20 0.71
TRPV4 Q9HBA0 1/20 0.71
TRPV2 Q9Y5S1 1/20 0.71
TRPM7 Q96QT4 1/20 0.65
DAGLA Q9Y4D2 1/20 0.65
MAOB P27338 4/20 0.61
APP P05067 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31545439 1.00 PPARG (0.71) PPARGCNR1CNR2TRPV1SLC6A3
SCHEMBL23537655 1.00 PPARG (0.71) PPARGCNR1CNR2TRPV1SLC6A3
SCHEMBL21864135 0.88 SLC6A3 (0.76) PPARGCNR1CNR2TRPV1SLC6A3
SCHEMBL24596011 0.85 SLC6A3 (0.76) PPARGCNR1CNR2TRPV1SLC6A3
Cannabigerol SCHEMBL14764730 0.83 PPARG (1.00) PPARGCNR1CNR2TRPV1SLC6A3
Cannabigerol SCHEMBL144819 0.83 PPARG (1.00) PPARGCNR1CNR2TRPV1SLC6A3
Cannabigerol SCHEMBL12954626 0.83 PPARG (1.00) PPARGCNR1CNR2TRPV1SLC6A3
SCHEMBL27206293 0.83 SLC6A3 (0.72) PPARGCNR1CNR2TRPV1SLC6A3
SCHEMBL24233347 0.83 SLC6A3 (0.72) PPARGCNR1CNR2TRPV1SLC6A3
SCHEMBL23888288 0.82 MAOB (0.80) PPARGCNR1CNR2TRPV1SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210276936-A1 Synthesis of Cannabigerol TREEHOUSE BIOTECH, INC. 2021-09-09 US disclosed
US-11040932-B2 Synthesis of cannabigerol TREEHOUSE BIOTECH, INC. (US) 2021-06-22 US disclosed
WO-2020249184-A1 SYNTHESIS AND PURIFICATION OF CANNABIGEROL AND ITS APPLICATION SYMRISE AG (DE) 2020-12-17 WO disclosed
US-20200115306-A1 SYNTHESIS OF CANNABIGEROL TREEHOUSE BIOTECH, INC. 2020-04-16 US disclosed
US-8124390-B2 Aromatic prenyltransferases, nucleic acids encoding same and uses therefor THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2012-02-28 US disclosed
US-20100285502-A1 NOVEL AROMATIC PRENYLTRANSFERASES, NUCLEIC ACIDS ENCODING SAME AND USES THEREFOR THE SALK INSTITUTE FOR BIOLOGICAL STUDIES TOUDAI TLO, LTD. 2010-11-11 US disclosed
US-7544498-B2 Aromatic prenyltransferases, nucleic acids encoding same and uses therefor THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2009-06-09 US disclosed
US-20080274478-A1 NOVEL AROMATIC PRENYLTRANSFERASES, NUCLEIC ACIDS ENCODING SAME AND USES THEREFOR THE SALK INSTITUTE FOR BIOLOGICAL STUDIES TOUDAI TOL, LTD. 2008-11-06 US disclosed
US-7361483-B2 Aromatic prenyltransferases, nucleic acids encoding same and uses therefor THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2008-04-22 US disclosed
CN-101137663-A Novel aromatic prenyltransferases, nucleic acids encoding same and uses thereof SALK INST FOR BIOLOGICAL STUDI (US) 2008-03-05 CN disclosed
US-20060183211-A1 Novel aromatic prenyltransferases, nucleic acids encoding same and uses therefor THE SALK INSTITUTE FOR BIOLOGICAL STUDIES TOUDAI TLO, LTD. 2006-08-17 US disclosed
WO-2006081537-A2 NOVEL AROMATIC PRENYLTRANSFERASES, NUCLEIC ACIDS ENCODING SAME AND USES THEREFOR THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2006-08-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200115306-A1 SYNTHESIS OF CANNABIGEROL COASY, ACSL3, SQLE PPARG 441/4885CNR1 76/4885CNR2 27/4885
US-11040932-B2 Synthesis of cannabigerol COASY, ACSL3, SQLE PPARG 441/4885CNR1 76/4885CNR2 27/4885
US-20210276936-A1 Synthesis of Cannabigerol COASY, ACSL3, SQLE PPARG 441/4885CNR1 76/4885CNR2 27/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.