Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 2/20 | 0.30 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7068729 | 0.88 | — | — | |
| SCHEMBL7068424 | 0.86 | TDP1 (0.33) | MEN1KMT2AKDM4EMAPTPOLB | |
| SCHEMBL7071591 | 0.81 | GAA (0.32) | MEN1KMT2AGAAALDH1A1BRD4 | |
| SCHEMBL7071341 | 0.77 | MEN1 (0.33) | MEN1KMT2AGAAALDH1A1BRD4 | |
| SCHEMBL7071722 | 0.76 | GAA (0.32) | MEN1KMT2AGAAALDH1A1BRD4 | |
| SCHEMBL7071625 | 0.75 | ALDH1A1 (0.40) | MEN1KMT2ASMN1; SMN2GAAKDM4E | |
| SCHEMBL7067258 | 0.73 | ALDH1A1 (0.35) | MEN1KMT2ASMN1; SMN2GAAKDM4E | |
| SCHEMBL7067905 | 0.73 | GAA (0.32) | MEN1KMT2AGAAALDH1A1BRD4 | |
| SCHEMBL7073504 | 0.73 | — | — | |
| SCHEMBL7066669 | 0.71 | BRD4 (0.34) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827498-B1 | NEW ANTIVIRAL SUBSTITUTED PYRIMIDINEDIONE HOMOCARBOCYCLIC NUCLEOSIDE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENTS | SAMJIN PHARM CO LTD (KR) | 2003-06-18 | — | — | EP | disclosed |
| US-5922727-A | 1-((SUBSTITUTED)CYCLOALK(EN)YLALKYL)-6-((SUB)PHENYL(CARBONYL, SULFIDE, OR OXO))-2,4-PYRIMIDINEDIONE DERIVATIVES HAVING SUPERIOR ANTIVIRAL ACTIVITIES; HIV | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 1999-07-13 | — | — | US | disclosed |