SCHEMBL7067972

SCHEMBL7067972

C#CCOP(=O)(O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.47
CA4 P22748 5/20 0.47
CA5A P35218 5/20 0.47
CA12 O43570 4/20 0.47
CA1 P00915 4/20 0.47
CA7 P43166 4/20 0.47
CA9 Q16790 4/20 0.47
CA5B Q9Y2D0 4/20 0.47
CFTR P13569 1/20 0.44
NPC1 O15118 1/20 0.42
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
TSHR P16473 2/20 0.40
ALDH1A1 P00352 2/20 0.40
DGAT1 O75907 1/20 0.40
ALOX15 P16050 1/20 0.37
USP2 O75604 1/20 0.37
GAA P10253 1/20 0.37
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11774074 0.82 MEN1 (0.44) CA2CA4CA5ACA12CA1
SCHEMBL11348721 0.81 CA2 (0.60) CA2CA4CA5ACA12CA1
SCHEMBL28661245 0.81 MEN1 (0.53) CA2CA4CA5ACA12CA1
SCHEMBL31096384 0.79 CYSLTR2 (0.38) CA2CA4CA5ACA12CA1
SCHEMBL15732278 0.78 CA2 (0.52) CA2CA4CA5ACA12CA1
SCHEMBL6888602 0.76 CA2 (0.50) CA2CA4CA5ACA12CA1
SCHEMBL27850950 0.75 CA2 (0.55) CA2CA4CA5ACA12CA1
SCHEMBL27436329 0.75 SRC (0.50) CA2CA4CA5ACA12CA1
SCHEMBL344619 0.75 ACHE (0.55) CA2CA4CA5ACFTRMEN1
SCHEMBL27502226 0.75 CFTR (0.48) CA2CA4CA5ACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118450798-A Ready-to-use barrier and knockdown pesticide 联合工业公司 2024-08-06 CN claimed
CN-118450798-A Ready-to-use barrier and knockdown pesticide 联合工业公司 2024-08-06 CN disclosed
CN-1117055-C Pesticide compounds, compositions and process for preparation thereof CHINOIN GYOGYSZER ES VEGYESZET (HU) 2003-08-06 CN disclosed
EP-0862545-B1 PESTICIDE COMPOUNDS, COMPOSITIONS AND PROCESS FOR THE PREPARATION THEREOF AGRO CHEMIE NOEVENYVEDOESZER G (HU) 2003-06-04 EP disclosed
CN-1206395-A Pesticide compounds, compositions and process for preparation thereof CHINOIN GYOGYSZER ES VEGYESZET (HU) 1999-01-27 CN disclosed
EP-0862545-A2 PESTICIDE COMPOUNDS, COMPOSITIONS AND PROCESS FOR THE PREPARATION THEREOF CHINOIN Gyògyszer és Vegyészeti Termékek Gyára RT. (HU) 1998-09-09 EP disclosed
WO-1997019040-A9 PESTICIDE COMPOUNDS, COMPOSITIONS AND PROCESS FOR THE PREPARATION THEREOF 1997-08-07 WO disclosed
WO-1997019040-A2 PESTICIDE COMPOUNDS, COMPOSITIONS AND PROCESS FOR THE PREPARATION THEREOF Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) 1997-05-29 WO disclosed
EP-0152229-B1 A CLASS OF PESTICIDES COMPRISING 1,4-BIS-SUBSTITUTED-2,6,7-TRIOXABICYCLO(2.2.2)OCTANES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1992-04-22 EP disclosed
US-3944666-A Insecticidal compositions and methods of combatting insects using 3-phenoxybenzyl 2,2-dimethyl-3-(2,2-dichlorovinyl)-cyclopropanecarboxylate insecticide with a synergistic compound of mono (alkyl and alkenyl)mono omega-alkynyl arylphosphonates FMC CORPORATION (US) 1976-03-16 US disclosed