Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 10/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 10/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.74 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.74 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | EBP | Q15125 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10508102 | 0.92 | CYP2D6 (0.70) | CYP2D6CYP2C9CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL18746335 | 0.92 | CYP2D6 (0.74) | CYP2D6CYP2C9CYP1A2CYP2C19CYP3A4 | |
| Hydrochloric Acid SCHEMBL10510793 | 0.91 | CYP2D6 (0.68) | CYP2D6CYP2C9CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL14129849 | 0.87 | CYP2D6 (1.00) | CYP2D6CYP2C9CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL14129854 | 0.85 | CYP2D6 (1.00) | CYP2D6CYP2C9CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL10575923 | 0.84 | CYP2D6 (0.76) | CYP2D6CYP2C9CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL14129968 | 0.83 | CYP2D6 (1.00) | CYP2D6CYP2C9CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL10511254 | 0.83 | CYP2D6 (0.64) | CYP2D6CYP2C9CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL6573617 | 0.82 | CYP2D6 (0.72) | CYP2D6CYP2C9CYP1A2CYP2C19CYP3A4 | |
| Hydrochloric Acid SCHEMBL10510495 | 0.82 | CYP2D6 (0.63) | CYP2D6CYP2C9CYP1A2CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4851526-A | ANTIARRYTHMIA, HYPOTENSIVE, ANTIISCHEMIC | SCHERING A.G. (DE) | 1989-07-25 | — | — | US | claimed |
| EP-0306440-A2 | 1-(4-substituted phenyl)-1H-imidazoles as cardiovascular agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-03-08 | — | — | EP | claimed |
| US-20030138376-A1 | Dosing form for reagents, use of said dosing form in organic chemical synthesis and production of said dosing form | H. LUNDBECK A/S (DK) | 2003-07-24 | — | — | US | disclosed |
| US-4851526-A | ANTIARRYTHMIA, HYPOTENSIVE, ANTIISCHEMIC | SCHERING A.G. (DE) | 1989-07-25 | — | — | US | disclosed |
| EP-0306440-A2 | 1-(4-substituted phenyl)-1H-imidazoles as cardiovascular agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-03-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030138376-A1 | Dosing form for reagents, use of said dosing form in organic chemical synthesis and production of said dosing form | ATIC, SET, SORD | CYP2D6 40/4885CYP2C9 135/4885CYP1A2 172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.