Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25420047 | 0.79 | FDPS (0.46) | FDPSTDP1GGPS1HTTSMN1; SMN2 | |
| SCHEMBL4969251 | 0.77 | FDPS (0.43) | FDPSTDP1GGPS1HTTLMNA | |
| SCHEMBL1293053 | 0.77 | TDP1 (0.52) | TDP1HTTLMNASMN1; SMN2ALOX15 | |
| SCHEMBL160156 | 0.74 | TDP1 (0.46) | TDP1HTTLMNASMN1; SMN2HSD17B10 | |
| SCHEMBL6048138 | 0.74 | TDP1 (0.46) | FDPSTDP1GGPS1HTTLMNA | |
| SCHEMBL158527 | 0.74 | KMT2A (0.46) | TDP1HTTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL3968932 | 0.73 | TDP1 (0.48) | TDP1HTTLMNASMN1; SMN2ALOX15 | |
| SCHEMBL491202 | 0.73 | HTT (0.50) | TDP1HTTLMNASMN1; SMN2HSD17B10 | |
| SCHEMBL8901472 | 0.73 | EGLN3 (0.46) | TDP1HTTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL6392854 | 0.73 | EGLN3 (0.46) | TDP1HTTSMN1; SMN2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003053989-A1 | MASKED PHOSPHATE CONTAINING NUCLEOSIDE DERIVATIVES AND THEIR USE AS ANTIVIRALS | MRC TECHNOLOGY LIMITED (GB) | 2003-07-03 | — | — | WO | disclosed |