Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.43 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | STAT6 | P42226 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25420047 | 0.82 | FDPS (0.46) | FDPSGGPS1ALOX15HSD17B10TDP1 | |
| SCHEMBL7068657 | 0.77 | FDPS (0.43) | FDPSGGPS1ALOX15HSD17B10TDP1 | |
| SCHEMBL595230 | 0.73 | FDPS (0.46) | FDPSP2RY2HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL27554271 | 0.71 | FDPS (0.47) | FDPSP2RY2HSD17B10KMT2ALMNA | |
| SCHEMBL8343857 | 0.71 | HDAC6 (0.38) | HSD17B10KDM4E | |
| SCHEMBL1293053 | 0.69 | TDP1 (0.52) | ALOX15HSD17B10TDP1HTTFGFR1 | |
| SCHEMBL8901472 | 0.68 | EGLN3 (0.46) | ALOX15HSD17B10TDP1EGLN3HTT | |
| SCHEMBL6392854 | 0.68 | EGLN3 (0.46) | ALOX15HSD17B10TDP1EGLN3HTT | |
| SCHEMBL9378132 | 0.67 | EGLN3 (0.49) | ALOX15HSD17B10TDP1EGLN3HTT | |
| SCHEMBL5613666 | 0.67 | RPS6KA5 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1777300-B1 | Organic salt additives for nucleic acid amplification | ROCHE DIAGNOSTICS GMBH (DE) | 2008-08-27 | — | — | EP | disclosed |