Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9480018 | 0.94 | ALDH1A1 (0.62) | KDM1AALDH1A1HSD17B10TDP1L3MBTL1 | |
| SCHEMBL2035896 | 0.94 | ALDH1A1 (0.62) | KDM1AALDH1A1HSD17B10TDP1L3MBTL1 | |
| Diphenylamine SCHEMBL11871615 | 0.87 | HSD17B10 (0.60) | KDM1AALDH1A1HSD17B10TDP1L3MBTL1 | |
| SCHEMBL222247 | 0.84 | ALDH1A1 (0.65) | KDM1AALDH1A1HSD17B10TDP1L3MBTL1 | |
| SCHEMBL9479616 | 0.84 | ALDH1A1 (0.65) | KDM1AALDH1A1HSD17B10TDP1L3MBTL1 | |
| SCHEMBL14819026 | 0.82 | ALDH1A1 (0.81) | ALDH1A1HSD17B10TDP1L3MBTL1TSHR | |
| SCHEMBL22620524 | 0.82 | ALDH1A1 (0.81) | ALDH1A1HSD17B10TDP1L3MBTL1TSHR | |
| SCHEMBL27315184 | 0.80 | ALDH1A1 (0.62) | KDM1AALDH1A1HSD17B10TDP1L3MBTL1 | |
| SCHEMBL9782622 | 0.78 | ALDH1A1 (0.59) | KDM1AALDH1A1HSD17B10TDP1L3MBTL1 | |
| SCHEMBL22198164 | 0.78 | ALDH1A1 (0.56) | KDM1AALDH1A1HSD17B10TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030192132-A1 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-10-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030192132-A1 | (P-amino-hydroxyphenyl)-acrylamide derivatives and dyes containing said compounds | KRT18, ALDH7A1, IK | KDM1A 2076/4885ALDH1A1 36/4885HSD17B10 1634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.