SCHEMBL222247

SCHEMBL222247

CN(C)c1ccc(Nc2ccc(N(C)C)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.65
TSHR P16473 4/20 0.65
ALOX15 P16050 2/20 0.65
HSD17B10 Q99714 2/20 0.65
KMT2A Q03164 5/20 0.52
GAA P10253 4/20 0.52
SMN1; SMN2 Q16637 4/20 0.52
MAPT P10636 3/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
KDM1A O60341 1/20 0.52
MAPK1 P28482 4/20 0.50
NPC1 O15118 4/20 0.50
TDP1 Q9NUW8 3/20 0.50
NPSR1 Q6W5P4 2/20 0.50
CYP3A4 P08684 2/20 0.50
TP53 P04637 2/20 0.50
RAB9A P51151 4/20 0.48
MEN1 O00255 4/20 0.48
ADRA2A P08913 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9479616 1.00 ALDH1A1 (0.65) ALDH1A1TSHRALOX15HSD17B10KMT2A
SCHEMBL469853 0.90 ALDH1A1 (0.71) ALDH1A1TSHRALOX15HSD17B10KMT2A
SCHEMBL11723882 0.90 ALDH1A1 (0.71) ALDH1A1TSHRALOX15HSD17B10KMT2A
SCHEMBL9480018 0.90 ALDH1A1 (0.62) ALDH1A1TSHRALOX15HSD17B10KMT2A
SCHEMBL2035896 0.90 ALDH1A1 (0.62) ALDH1A1TSHRALOX15HSD17B10KMT2A
SCHEMBL80012 0.88 ALDH1A1 (0.73) ALDH1A1TSHRALOX15HSD17B10KMT2A
SCHEMBL3893822 0.88 APP (0.57) ALDH1A1TSHRALOX15HSD17B10KMT2A
Hydrochloric Acid SCHEMBL11738417 0.86 APP (0.55) ALDH1A1TSHRALOX15HSD17B10KMT2A
SCHEMBL3223775 0.84 MAPT (0.71) ALDH1A1HSD17B10KMT2AGAASMN1; SMN2
SCHEMBL7068792 0.84 KDM1A (0.54) ALDH1A1TSHRALOX15HSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 414 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304541-A1 METHYLENE BLUE HAVING A REDUCED CONTENT OF N-NITROSO-AZURE B IMPURITY AND PROCESS FOR OBTAINING THE SAME Icrom S.R.L. (IT) 2025-10-02 US claimed
CN-116199662-B Visible light and near infrared light rhodamine fluorescent quenching agent and synthesis and application thereof 中国科学院大连化学物理研究所 2024-10-11 CN claimed
CN-114685318-B Preparation method of N- (carboxymethyl aminocarbonyl) -4,4' -bis (dimethylamino) diphenylamine sodium salt 苏州络森生物科技有限公司 2024-03-29 CN claimed
WO-2023212547-A1 PHENYL CONTAINING SORBENTS, BICARBONATE CONTAINING SORBENTS, SYSTEMS INCLUDING SORBENTS, AND METHODS USING THE SORBENTS GLOBAL THERMOSTAT OPERATIONS, LLC. (US) 2023-11-02 WO claimed
CN-116199662-A Visible light and near infrared light rhodamine fluorescent quenching agent and synthesis and application thereof 中国科学院大连化学物理研究所 2023-06-02 CN claimed
CN-114685318-A Preparation method of N- (carboxymethyl aminocarbonyl) -4,4' -bis (dimethylamino) diphenylamine sodium salt 苏州络森生物科技有限公司 2022-07-01 CN claimed
US-11261282-B2 PEO-PPO-PEO triblock bipolymers, with amphoteric endings, as demulsifying agents for heavy crude oils INSTITUTO MEXICANO DEL PETROLEO (MX) 2022-03-01 US claimed
US-11261403-B2 Stabilized compositions comprising leuco compounds MILLIKEN & COMPANY (US) 2022-03-01 US claimed
US-11136535-B2 Leuco colorants as bluing agents in laundry care compositions THE PROCTER & GAMBLE COMPANY (US) 2021-10-05 US claimed
EP-3830232-A1 LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS The Procter & Gamble Company (US) 2021-06-09 EP claimed
US-7094897-B2 Rhodium and iridium complexes COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2006-08-22 US claimed
US-20060065890-A1 Rhodium and iridium complexes COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2006-03-30 US claimed
EP-1379534-B1 RHODIUM AND IRIDIUM COMPLEXES COVION ORGANIC SEMICONDUCTORS (DE) 2004-12-15 EP claimed
EP-0926244-B1 METHODS AND REAGENTS FOR QUANTITATIVELY DETERMINING ASCORBIC ACID KYOWA MEDEX CO LTD (JP) 2004-11-17 EP claimed
US-20040133004-A1 Rhodium and iridium complexes MERCK PATENT GMBH (DE) 2004-07-08 US claimed
US-6153399-A SIMPLE METHOD FOR QUANTITATIVE DETERMINATION IN SAMPLE BY REACTING IN AQUEOUS MEDIUM ASCORBIC ACID, OXYGEN, ASCORBATE OXIDASE, CHROMOGEN, AND PEROXIDASE; MEASURING ABSORBANCE; COMPARING WITH A CALIBRATION CURVE KYOWA MEDEX CO., LTD. (JP) 2000-11-28 US claimed
EP-0926244-A1 METHODS AND REAGENTS FOR QUANTITATIVELY DETERMINING ASCORBIC ACID KYOWA MEDEX CO., LTD. (JP) 1999-06-30 EP claimed
US-4870049-A TRANSFER SHEET FOR THERMAL PRINTING SHARP KABUSHIKI KAISHA (JP) 1989-09-26 US claimed
US-4752119-A Electrochromic display devices NEC CORPORATION (JP) 1988-06-21 US claimed
US-4187105-A Photosensitive image forming composition containing at least one substituted bis-diaryl vinylidene compound and/or at least one substituted bis-diaryl imine compound HORIZONS RESEARCH INCORPORATED (US) 1980-02-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060065890-A1 Rhodium and iridium complexes RPIA, INPP5B, SIRT5 ALDH1A1 1107/4885TSHR 3136/4885ALOX15 4012/4885
US-20040133004-A1 Rhodium and iridium complexes RPIA, SIRT5, INPP5B ALDH1A1 1115/4885TSHR 2691/4885ALOX15 3925/4885
US-20250304541-A1 METHYLENE BLUE HAVING A REDUCED CONTENT OF N-NITROSO-AZURE B IMPURITY AND PROCESS FOR OBTAINING THE SAME MMAB, HBB, MB ALDH1A1 702/4885TSHR 3182/4885ALOX15 462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.