Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 8/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066317 | 0.83 | KMT2A (0.47) | — | |
| SCHEMBL28626965 | 0.78 | AAK1 (0.46) | AAK1HDAC1 | |
| SCHEMBL7068930 | 0.77 | AAK1 (0.42) | AAK1HDAC1PPARGPPARAERAP2 | |
| SCHEMBL246277 | 0.76 | AAK1 (0.46) | AAK1HDAC1 | |
| SCHEMBL29765467 | 0.76 | AAK1 (0.46) | AAK1HDAC1 | |
| SCHEMBL5563026 | 0.73 | KCNQ3 (0.45) | AAK1HDAC1CYP17A1 | |
| SCHEMBL5563988 | 0.72 | CYP1A2 (0.45) | AAK1HDAC1S1PR3CYP17A1 | |
| SCHEMBL6492339 | 0.72 | BRD4 (0.46) | AAK1LTA4H | |
| SCHEMBL15160030 | 0.71 | GAA (0.52) | AAK1CYP17A1 | |
| SCHEMBL3410364 | 0.71 | HPGD (0.49) | AAK1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |