Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7068935 | 0.83 | AAK1 (0.41) | — | |
| SCHEMBL28885280 | 0.80 | MAPT (0.61) | KMT2AMEN1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL7066309 | 0.79 | RAB9A (0.47) | KMT2AMEN1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL977967 | 0.78 | MEN1 (0.66) | KMT2AMEN1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL5563288 | 0.75 | MEN1 (0.50) | KMT2AMEN1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL5562070 | 0.75 | KMT2A (0.50) | KMT2AMEN1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL7065219 | 0.74 | IDO1 (0.38) | KMT2AMEN1SMN1; SMN2MAPTPKM | |
| SCHEMBL7130856 | 0.74 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL8664998 | 0.74 | TDP1 (0.56) | KMT2AMEN1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL31365089 | 0.74 | ALDH1A1 (0.58) | KMT2ASMN1; SMN2RAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |